芳香甲基酮sp3 C-H活化和二聚偶联合成(E)-1,4-二酮

摘要

(E)-1,4-Enediones were synthesized efficiently via sp3 C-H activation and dimerization coupling of aromatic methyl ke-tones,using palladium acetate as catalyst,copper bromide as oxidant in N,N-dimethylformide. The transformation had a broad sub-strate scope.%通过芳香甲基酮的sp3C-H活化和二聚偶联有效地合成了(E)-1,4-二酮.在DMF中用醋酸钯作催化剂,溴化铜为氧化剂,该反应具有广泛的底物范围.