目的 了解北京市朝阳区60岁及以上老年人HBsAg流行状况和抗-HBs水平.方法 2014年在朝阳区43个社区采用年龄性别等比例抽样的方法 ,选取60岁及以上的常住居民,通过面对面问卷调查了解乙肝感染的相关特征及影响因素,采集静脉血通过酶联免疫吸附实验试剂检测HBsAg和抗-HBs.结果 共调查27 183人,HBsAg粗阳性率为2.01％(95％CI:1.84％ - 2.18％).年龄别的HBsAg阳性率随年龄上升呈现下降趋势,男性HBsAg阳性率(2.08％)和女性(1.96％)相比差异无统计学意义(P＞ 0.05);北京户籍者HBsAg阳性率(1.80％)低于外地户籍者(3.46％)(P＜0.01).抗-HBs 粗阳性率为29.55％(95％CI:29.01％-30.09％),北京户籍者抗-HBs 阳性率(28.02％)低于外地户籍者(38.36％)(P＜0.01).结论 朝阳区60岁以上京籍老年人HBsAg 流行率已处于较低水平,但非京籍人群HBsAg感染率相对较高,朝阳区老年人乙肝防控的重点应为外地户籍人口.%Objective To determine the seroepidemiology of HBV infection and HBV immunity among adults aged 60 years and older in Chaoyang district of Beijing. Methods The residents aged 60 years and older were selected by the sex and age proportional sampling method from 43 communities in Chaoyang district of Beijing in 2014. A questionnaire-based interview was performed to explore the characters and associated factors. The venous blood specimens were collected to test HBsAg and anti-HBs by ELISA. Results A total of 27 183 residents were surveyed. The overall positive rate of HBV surface antigen (HBsAg) was 2. 01％ (95％CI: 1. 84％ - 2. 18％) . These rates among age groups decreased with increasing age. There was no significant difference between menand women in positive rate of HBsAg (2. 08％ vs. 1. 96％,P＞0. 05) . For local residents group and mobile population group,the positive rate of HBsAg was 1. 80％ and 3. 46％ (P＜ 0. 01) . The overall positive rate of anti -HBs was 29. 55％ (95％CI: 29. 01％-30. 09％) . This rate in local residents was lower than that in others (28. 02％ vs. 38. 36％,P＜0. 01) . The overall negative rate of HBsAg and anti-HBs was 68. 57％ (95％CI: 68. 02％-69. 12％) . Conclusion The prevalence of HBV infection among local residents aged 60 years and older in Chaoyang district has reached a low level,but it was relatively higher among mobile population. HBV prevention among the old in Chaoyang district should focus on the mobile population.
展开▼
