Objective To evaluate the safety of tooth extraction in the cardiovascular disease patients under local anesthesia with articaine. Methods A total of 1224 patients were included in this study. The changes of systolic (SBP) and diastolic (DBP) blood pressure,heart rate, electrocardiogram (EEG) and subjective feeling were observed before, during and after operation. Results Tooth extraction in all patients was successfully completed. SBP, DBP and heart rate increased significantly during operation ( P ＜ 0. 05 ) and decreased 10 minutes after tooth extraction ( P ＜ 0. 01 ). Conclusion Tooth extraction is safe for properly treated patients with cardiovascular disease under local anesthesia.%目的 探讨应用含微量肾上腺素的阿替卡因局部麻醉药对心血管病患者拔牙的安全性.方法 对1224名心血管病患者应用含微量肾上腺素的局部麻醉药,在心电监护下拔牙,观察并监测手术过程中麻醉前后、拔牙前后的血压、心率变化,进行对比分析.结果 1224名患者均较顺利完成手术;麻醉前、后,麻醉前与拔牙术中,拔牙术中、术后及麻醉前与拔牙术后10min的收缩压变化均有统计学差异;拔牙后10min的收缩压、舒张压及心率较麻醉前显著下降.结论 对经过全身系统治疗、病情稳定的心血管病患者,麻药中加入少量肾上腺素局麻下拔牙是安全有效的.
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