肿瘤是一种系统生物学疾病,治疗这一顽固疾病仅靠单一靶向药物已不太现实。本文将用系统生物学的观点,对肿瘤坏死因子相关凋亡配体( TRAIL)与现今研究较热点的靶向药物以网络“network”联合方式,协同抗肿瘤进行一个综述。以期待为基于TRAIL个体化治疗肿瘤提供夯实的理论依据。%Tumor is a system-biology illness.Treatment of this intractable disease by any single medicine has not been realistic.In this review, we analyze the anti-tumor network of Tumor Necrosis Factor-related Apoptosis-indu-cing Ligand ( TRAIL ) by a system-biology technology and try to providecin individualized treatment strategy for TRAIL based therapy .
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