从神经炎症发病机制探讨中医药治疗帕金森病的思路

摘要

从神经炎症发病机制探讨中医药治疗帕金森病的思路与方法, 以"毒损脑络"病机理论与神经炎症发病机制的相关性为切入点, 结合神经炎症的产生机制及其在帕金森病中的作用, 通过理解中医学中毒邪与神经炎症的关系及在帕金森病中作用的病机, 从毒邪立论探讨中医治疗帕金森病的思路与方法.神经炎症是帕金森病炎症反应的病理基础, 并贯穿帕金森病炎症反应的始终.神经炎症因子的作用与中医学"肾虚髓衰、脑络瘀阻、毒损脑络"观点相一致.中医解毒通络、补脾益肾、调畅神机法可抑制神经炎症因子在帕金森病中的致病作用, 值得更深入的临床探讨研究.%To explore the idea and method of TCM treatment of Parkinson's disease (PD) from the pathogenesis of neuroinflammation.The relationship between the pathogenesis of"poisonous brain network" and the pathogenesis of neuroinflammation was taken as the breakthrough point.Combined with the mechanism of neuronal inflammation and its role in PD, by understanding the relationship between"poisonous evil" and" Relationship and the role of the pathogenesis in the PD, from the venom to discuss the traditional Chinese medicine treatment of PD ideas and methods.Neuritis is the pathogenesis of the inflammatory response of PD and is consistent throughout the inflammatory response of PD.The role of neuroinflammatory factors and traditional Chinese medicine"Kidney empty marrow failure, Obstruction of brain Luo, toxin damaging luo of brain" point of view consistent.Chinese Medicine"removingtoxin and activatingcollaterals, invigorating spleen and kidney, protect the brain network, adjust the god machine method", can inhibit the neuroinflammatory factor in the pathogenesis of PD, it is worth further study.