2-氯-5-碘苯甲酸的合成

摘要

2-Chloro-5-iodobenzoic acid was synthesized from ethyl-o-aminobenzoate by three-step reaction of iodination ,Sandmeyer reaction and hydrolyzation. The total yield was 50.2% ,the structure was characterized by 'H NMRJR and MS.%以邻氨基苯甲酸甲酯为原料,经碘代、桑德迈尔反应、水解三步反应合成了2-氯-5-碘苯甲酸,总收率50.2％,其结构经1H NMR,IR和MS表征.