重组人干扰素α-2b辅助治疗婴幼儿毛细支气管炎疗效观察

摘要

目的 观察重组人干扰素α-2b辅助治疗婴幼儿毛细支气管炎的临床疗效.方法 112例2月～2岁的毛细支气管炎患儿随机分为治疗组59例和对照组53例,两组患儿均给予抗感染,抗病毒,雾化吸入及其他支持,对症治疗,治疗组加用重组人干扰素α-2b,观察两组咳嗽,喘息,肺部湿罗音,哮鸣音消失时间及疗效评价.结果 治疗组咳嗽,喘息,肺部湿罗音,哮鸣音消失时间明显短于对照组,治疗组总有效率96.6%,对照组总有效率84.9%,差异具有统计学意义(P<0.05).结论 肌肉注射重组人干扰素α-2b辅助治疗毛细支气管炎安全,有效.%Aim To investigate the efficacy of candesartan and amlodipine on primary hypertension with early renal damage. Methods 83 microalbuminuria positive outpatients with essential hypertension( 1,2 )were divided into amlodipine group( 5 mg · d -1 )with 42 cases and candesartan group( 8 mg · d -1 )with 41 cases according to the order of visits,with a course of 3 months. The difference was observed in blood pressure,Scr,UMALB, Uαl- MG and CystC before and after treatment. Results Blood pressure of the two groups descended more significantly than those before treatment( P ＜ 0.01 ), but comparing the blood pressure between the two groups after treatment,the difference is not significant( P ＞ 0.05 );Scr of the two groups had no changes before and after treatment( P ＞ 0.05 ); UMALB and CystC of the two groups are lower than those before treatment( P ＜ 0.05 ),and the candesartan group was better than amlodipine group( P ＜ 0.05 ). So are Uαl- MG of the two groups,with a significant drop( P ＜ 0.01 ). Conclusion Both candesartan and amlodipine have a good antihypertensive effect to reduce levels of UMALB,Uαl-MG and CystC,but the effect of candesartan is better than that of amlodipine on primary hypertension with early renal damage.