2b Soluble overexpression and purification method of bioactive recombinant human interferon alpha 2b

摘要

The present invention relates to a water-soluble overexpression and purification method of a human interferon alpha 2b (IFN -2b) having biological activity, wherein a recombinant expression including a solubility enhancing tag and an IFN -2b gene Vector. Also provided is a recombinant microorganism transformed with the recombinant expression vector, and provides a method for producing the IFN -2b recombinant protein. The purified IFN -2b protein according to the present invention is expected to play an important role as a broad therapeutic agent for viral diseases.;