临床药师干预清洁手术围手术期预防性应用抗菌药物的对比分析

摘要

Objective To assess the effect of clinical pharmacist's intervening in the antibiotic medicine application for thyroid surgery,breast surgery and hernia repair surgery (3 cleaning operations).Methods A total of 189 cases (before the intervention)which un-derwent the above three cleaning operations in the Department of General Surgery and were discharged in the time period from Jan.2012to Jun.2012 from Huaibei Miners'General Hospital were collected,and 165 cases discharged from hospital from Jul.2012 to Dec.2012(after the intervention)were chosen.The rationality of preventative application for antibiotics was analyzed.Results After the inter-ventions by the clinical pharmacists,the preventative application of medicine for cleaning surgery was improved obviously compared withpre-intervention in aspects of the indications,medicine selection,dose,timing for medication,route of administration,the menstruum ofmedicine selection.Conclusions The intervention in the preventative application of antibiotics by the clinical pharmacists is feasibleand effective,which can improve the rational application of antibiotics ,decrease medical cost,and promote safe,effective,and economi-cal use of antibiotics.%目的：临床药师对医院三种Ⅰ类清洁手术（甲状腺手术、乳腺手术、疝气修补术）抗菌药物预防应用的干预效果评价。方法分别抽取普外科2012年1-6月份出院的三种Ⅰ类清洁手术干预前病例189例和2012年7-12月份出院的三种Ⅰ类清洁手术干预后病例165例，对抗菌药物预防应用的临床合理性进行评价。结果经过临床药师干预，清洁手术围术期患者预防应用抗菌药物在临床适应证、药物的选择、用法用量、用药时机、给药途径、溶媒选择等各方面较干预前均得到明显改善。结论临床药师对围术期预防应用抗菌药物进行干预的方法是可行和有效的，能促进临床合理使用抗菌药物，优化医疗资源使用，对促进抗菌药物临床安全、有效、经济的应用可起到良好的效果。