自由基清除剂依达拉奉的药理作用研究进展

摘要

依达拉奉是目前临床唯一使用的自由基清除剂，主要用于治疗缺血性脑卒中。最新研究表明，依达拉奉的药理作用涉及多个方面且临床应用不仅仅局限于治疗缺血性脑卒中。该文就依达拉奉对脑、心脏、肝脏、肺等器官损伤的保护的药理作用研究进展进行综述，旨在为进一步开发依达拉奉的新用途提供依据。%Edaravone ,a free radical scavenger ,has been used for the treatment of acute cerebral ischemic stroke .Recent researches show that the pharmacological effect of edaravone may involve many organs and its clinical application is not limited to ischemic stroke .This article reviewed the pharmacological progress in the protective effects of edaravone on different organ injuries (brain,heart,liver,lung, etc.) in order to provide evidence for the novel clinical applications of edaravone in future .