益气养阴活血法改善2型糖尿病病人脂质代谢紊乱的临床观察

摘要

目的 观察益气养阴活血中药对2型糖尿病合并脂质代谢紊乱病人血糖、血脂水平的影响.方法 将48例2型糖尿病合并脂质代谢紊乱的病人随机数字表法为对照组和治疗组,两组病人在饮食、运动等生活方式干预的基础上,对照组继续使用西药降糖治疗;治疗组在西药基础上加用益气养阴活血中药丹蛭降糖胶囊.观察治疗前后血糖、糖化血红蛋白、血脂总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)等指标的变化.结果 与对照组比较,给予丹蛭降糖胶囊干预后治疗组病人血糖、糖化血红蛋白、TC、TG、LDL-C水平显著降低(P<0.05),HDL-C 水平显著升高(P<0.05).结论 益气养阴活血中药可能通过改善脂肪细胞的分化功能,降低血清脂质,减小脂肪细胞体积,增强脂肪细胞的贮脂能力,临床能获得较好的疗效.%Objective To observe the effect of bvqnyabc on blood glucose and blood lipid levels of type 2 diabetes mellitus patients with lipid metabolism disorder.Methods Forty-eight patients with type 2 diabetes mellitus and lipid metabolism disorder were randomly assigned into control group and treatment group.On the basis of diet and sports intervention in both groups,the patients in the control group received hypoglycemic treatment with Western medicine,while the treatment group received Western medicine combined with an additional traditional Chinese medicine Danzhijiangtang capsule.Observation was performed on the changes of blood glucose,glycosylated hemoglobin,total cholesterol (TC),triglyceride (TG),high density lipoprotein cholesterol (HDL-C),low density lipoprotein cholesterol (LDL-C) and other indicators before and after treatment.Results Compared with the control group,the intervention group had significantly decreased blood glucose,glycosylated hemoglobin,TC,TG,LDL-C (P<0.05),and significantly increased HDL-C (P<0.05) after treatment.Conclusions Traditional Chinese medicine may improve the differentiation of adipose cells,reduce serum lipid and the volume of adipose cells,enhancelipid storage capacity of adipose cells,which achieves a good outcome in clinic.