经皮左心耳封堵装置预防心房颤动血栓新进展

摘要

Atrial fibrillation (AF),one of the most common arrhythmias in clinical,is an independent risk factor for ischemic stroke,and it is easy to form thrombus in left atrial appendage (LAA) after causing hemodynamic disorder.The treatment objectives in patients with AF contain eliminating AF and preventing stroke.Apart from the methods of pharmacological or electricity cardioversion,radiofrequency ablation,oral anticoagulation,percutaneous LAA closure is a new technique of closing the LAA to prevent stroke in AF patients,and it can help patients who are not applicable or tolerate the long-term to warfarin anticoagulation.This article reviews the advances in percutaneous left atrial appendage closure in atrial fibrillation.%心房颤动是临床上最常见的心律失常之一,造成血流动力学紊乱后易在左心耳处形成血栓,是脑卒中的独立危险因素.目前心房颤动的主要治疗策略是消除心房颤动和预防脑卒中,经皮左心耳封堵术是在传统药物、电复律、射频消融、口服抗凝药之外近年来发展的通过微创导管术封堵左心耳以达到预防心房颤动病人血栓栓塞的新技术,帮助有抗凝治疗禁忌的非瓣膜性心房颤动病人安全有效地预防脑卒中的发生.该研究就经皮左心耳封堵术在心房颤动中的应用进展进行综述.