Presepsin在新生儿败血症诊断中的研究进展

摘要

在发展中国家,新生儿败血症的发生率逐年增加,近年研究发现一种新的标记物,即Presepsin(可溶性CD14分子亚型,sCD14-T).其在成人脓毒症诊断与评价的研究中显示了良好的临床意义,因此在生物标记中,Presepsin很可能是反映机体脓毒症严重程度的最好指标.该文就Presepsin本身及其在新生儿败血症领域的相关研究进行综述.%The incidence of neonatal sepsis has increased in the developing world.In recent years,the study found a new marker,named soluble or Presepsin (sCD14-T).In the diagnosis and evaluation of adult sepsis,it shows good clinical value,so the Presepsin is likely to be the best index reflecting the severity of sepsis body in biomarkers.In this paper,the study of Presepsin and its related research in the field of neonatal sepsis were summarized.