Objective To know interrupting mother-to-infant transmission knowledge, attitude and practice (KAP) of the pregnant women infected with hepatitis B virus( HBV) in Hefei and analyze the influence factors, so as to provide basis for the health education of hep-atitis B prevention. Methods The questionnaire was self-designed and 200 individuals were investigated by random sampling from four dis-tricts in Hefei and 169 questionnaires were effective. The influence factors of KAP scores were analyzed by t-test and logistic regression mod-el. Results The KAP scores was generally low. The average score was (5. 20 ± 2. 24) and the passing rate was 47. 31%. The influence factors of KAP included educational level, areas and infected time and so on. The KAP scores was lower in the pregnant women whose educa-tional level was low, whose residence was rural, whose mother did not know if she had been infected and whose infected time was short. Con-clusion We should carry out diversified health education according to the characteristics of the pregnant women infected with HBV, so as to improve their KAP level.%目的：了解合肥市乙肝感染孕妇母婴阻断知识、信念、行为( KAP)状况，并对其影响因素进行分析，为开展乙肝预防健康教育提供依据。方法自行设计问卷，在合肥市四个区随机抽取200名乙肝感染孕妇，回收有效问卷169份。采用t检验、logistic回归分析对乙肝感染孕妇KAP得分的影响因素进行分析。结果乙肝感染孕妇KAP得分总体较低，平均得分为(5．20±2．24)分，及格率为47．31%。分析显示影响乙肝感染孕妇KAP的因素包括学历、居住地、被感染时间等，大专以下学历、居住地在农村的孕妇、母亲不知道自己是否乙型肝炎病毒感染者的孕妇及被感染时间短的孕妇KAP得分较低。结论公共卫生服务机构应根据乙肝感染孕妇的特征，针对性开展多种形式的健康教育，有效提高乙肝感染孕妇KAP水平。
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