LDL-C／HDL-C及TG／HDL-C比值与冠状动脉病变程度的相关性研究

摘要

目的：探讨LDL-C／HDL-C及TG／HDL－C比值与冠心病病变程度之间的相关性。方法分析169例冠脉造影检查确诊的冠心病患者（ CHD组）及103例冠脉造影结果阴性者（对照组） LDL－C／HDL－C及TG／HDL－C比值与冠心病及其病变程度的关系。结果冠心病组患者LDL－C／HDL－C比值及TG／HDL－C比值水平及异常率均明显高于对照组，相关分析显示：LDL-C／HDL-C及TG／HDL-C比值与冠心病及其病变程度均呈正相关，而前者预测意义更大。结论 LDL-C／HDL-C及TG／HDL-C比值可作为预测CHD的指标，且LDL-C／HDL-C比值水平与CHD相关性更强。%Objective To explore the correlation between LDL-C/HDL-C and TG/HDL-C ratio and severity of coronary heart dis-ease.Methods LDL-C/HDL-C and TG/HDL-C ratio was analysed in 272 geriatric cases that underwent coronary angiography, who were positive in 169 geriatric patients(CHD group),and negative in 103 cases(normal control group).Results Both LDL-C/HDL-C and TG/HDL-C ratio and its abnormal rate were significantly higher in patients with CHD than those in the normal control group(P<0.05).Correla-tion analysis and multivariate regression analysis revealed that the ratio had significant positive correlation with coronary heart disease and its severity.Conclusion LDL-C/HDL-C and TG/HDL-C ratio is a good predictive index for CHD.Compared to TG/HDL-C ratio,LDL-C/HDL-C ratio reveals stronger correlation with CHD.