Hyperhomocysteinmia is a risk factor of cardiovascular diseases such as coronary heart disease and stroke. Hypertension with elevated plasma homocysteine is defined as H type hypertension. It accounts for about 75% in Chinese hypenensive patients. Lowering both blood pressure and plasma homocysteine level is recommended in H type hypertension therapy. The most effective way to decrease homocysteine level is folic acid supplementation, and it may reduce the risk of cardiovascular events.%高同型半胱氨酸血症是冠状动脉粥样硬化性心脏病、脑卒中等心脑血管疾病的危险因素,伴有血浆同型半胱氨酸水平升高的高血压被定义为"H型"高血压,约占我国成年高血压患者的75%."H型"高血压的治疗应同时降低血压和血浆同型半胱氨酸的水平.降低同型半胱氨酸最有效的方法是补充叶酸,并可能减少心脑血管事件的发生.
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