经导管卵圆孔未闭封堵术后残余分流影响因素及研究现状分析

摘要

卵圆乳未闭(PFO)是最常见的一种右向左分流的通道,与矛盾性栓塞密切相关.经皮PFO封堵术作为治疗PFO合并矛盾性栓塞的重要治疗手段,可减少及消除右向左分流、预防再发性神经系统栓塞事件的发生.现总结PFO右向左分流的检测方法、封堵术后残余分流与再发性神经系统栓塞事件的关系、预测因子及治疗方法.%Patent foramen ovale is the most common cause of right-to-left shunt(RLS),which is closely associated with paradoxical embolism.Transcatheter patent foramen ovale(PFO) closure has been proposed as an alternative for secondary prevention of paradoximal embolism.Reduction or complete abolition of RLS and prevention of recurrent neurology embolism event (RNEE) represent the primary targets of the intervention.This article summarizes the methods on detecting of RLS,the relation between residual right-to-left shunt (rRLS) after PFO closure and RNEE,predictors and management of rRLS.