Objective To evaluate the clinical therapeutic effect of acupoint-catgut-embedment therapy in the treatment of mammary gland hyperplasia (MGH).Methods Eighty MGH patients were equally randomized into acupoint-catgut-embedment (ACE) group and medication (Rupixiao, a herbal patent drug for relieving MGH) group according to odd-numbered days or even-numbered days of visiting.Subcutaneous catgut-embedment was performed in Wuyi (ST 15), Rugen (ST 18), Tanzhong (CV 17), Xuehai (SP 10), Zusanli (ST 36) and Yanglingquan (GB 34), once every 15 days for 3 months.Patients of the medication group were treated by oral administration of Rupixiao (3 tablets, 3 times per day, 3 months altogether).The degree of breast pain and the size of the hyperplastic lump were observed before and after the treatment.Serum estrodiol, progesterone and prolactin contents on day 1 to day 3 of menstruation were detected by using an automation chemiluminescence immune analysator.Results After the treatment, of the two 40 MGH patients in the ACE and medication groups, 16 (40.0％) and 5 (12.5％) were cured basically, 8 (20.0％) and 8 were improved markedly in their symptoms and signs, 16 (40.0％) and 22 (55.0％) were effective, and 0 and 5 (12.5％) failed in the treatment, with the effective rates being 100％ and 87.5％, respectively.The therapeutic effect of the ACE group was significantly better than that of the medication group (P＜0.05).In comparison with the pretreatment, the pain grades and the size of the hyperplastic lump in both ACE and medication groups decreased significantly after immediate termination of the treatment and 6 months after the treatment (P＜0.01), and the therapeutic effects of the ACE group were significantly superior to those of the medication group in reducing pain grade and hyperplastic lump size (P＜0.01).After the treatment, serum estrodiol and progesterone contents were decreased evidently in both ACE and medication groups (P＜0.01, P＜0.05).Type-B ultrasonic examination showed that of the two 40 MGH patients in the ACE and medication groups,16 and 5 cases turned to normal in their mammary glands, and the cure rate of the ACE group was evidently higher than that of the medication group (P＜0.01 ).Conclusion Acupoint-catgut-embedment is effective in relieving MGH, and its therapeutic effect is apparently superior to that of medication (oral administration of Rupixiao).%目的:观察穴位埋线治疗乳腺增生病的临床疗效.方法:将所选乳腺增生病病例按就诊单双日分为穴位理线组(单日)40例和口服乳癖消对照组(双日)40例.穴位埋线选择屋翳、乳根、腹中、血海、足三里、阳陵泉穴,15d理线1次,6次为一疗程,共治疗1个疗程.观察两组1个疗程后近期疗效和6个月后随访远期疗效(包括乳房疼痛程度和肿块大小),并检测治疗前后患者卵泡期雌二醉、孕酮、泌乳素以及乳腺B超.结果:埋线组总有效率明显优于对照组(P<0.05),两组近期、远期疗效(疼痛分级、肿块大小)显著(P<0.01),埋线组仍明显优于对照组(P<0.01);埋线组降低雌二醉含量的效应优于对照组(P<0.01),乳腺B超改善埋线组优于对照组(P<0.01).结论:穴位埋线治疗乳腺增生病近期、远期疗效显著,优于口服乳癖消.
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