In the present paper it is rcported that glycolipid was successfully inserted into colorchangeable TCDA/DGG and PCDA/DGG polydiacetylene vesicles based on physical force rather than covalent binding. And the effects on polyinerization of diacetylene and the change of the polymer vesicles’ color due to the relative quantity of glycolipid versus diacctylene molecules were also reported. The experimental results demonstrated that this approach is available and the colorchangeable property of such polydiacetylenic vesicles was not affected due to the inceorporation of glycolipid. This provided a simple and useful method of functonalizing the polymer vesicles for their wide applications.
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