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登革热全球流行势态及对策

         

摘要

Currently, the dengue virus and its vectors have now become widely distributed throughout tropical and subtropical regions of the world. The expansion of dengue is expected to increase due to factors such as climate change, globalization,international travel and trade,socioeconomics,settlement and dengue viral evolution. Transmission of dengue is now present in more than 125 countries known to be dengue endemic. Estimates of the global incidence of dengue infections annually have ranged between 50 million and 200 million; however, recent estimates using cartographic approaches suggest the data is closer to 400 million. Currently no vaccine or specific antiviral therapy exists to address the growing threat of dengue. Prompt case detection and appropriate clinical management can reduce the mortality from severe dengue. Effective vector control is the mainstay of dengue prevention and control. In order to control the risk of imported dengue fever,the general countermeasure includes two aspects:firstly,it is necessary to provide accurate dengue infection risk assessment to those who exit the dengue epidemic area,implementation of dengue fever prevention by health education on personal protection at the same time, especially for the staff or labors export abroad and study abroad; Then, it' s important to trigger early warning monitoring mechanism at the ports of entry and exit and quarantine, and to minimize the risk of dengue fever spread as soon as possible.%当前,登革病毒及其媒介伊蚊已遍布全球热带和亚热带地区.气候变暖、全球化、国际旅行、人居环境改变和病毒变异等,是导致登革热不断扩张的主要因素.现在,登革热已经遍布全球六大世界卫生组织区域,超过125个国家成为登革热地方性流行疫区.迄今为止,全球每年登革热的发病率估计波动在0.5~2亿之间,制图法评估发病率则接近4亿.目前尚无疫苗预防或特异性抗病毒药对治登革热,快速病例检测和临床治疗能够降低重症病例死亡率,而媒介蚊虫控制是现今预防和控制登革热流行的主要手段.为防控输入性登革热传入内陆口岸,总体防控措施为:一是对前往登革热疫区的出境人员及提供准确的登革热疫情评估通告,特别是针对重点人群,即劳务输出人员和出境留学人员,开展登革热防护的健康教育,降低个人感染风险;二是建立完善的疫情预警监测机制,及时做好出入境人员及货物等携带媒介生物的检验检疫,将输入性登革热的传播风险降到最低.

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