为了研究大肠杆菌对仔兔小肠形态学影响,比较不同治疗方法的效果.将40只仔兔随机平均分为4组.经腹腔注射菌液后检测不同时期内毒素含量,并观察和比较小肠形态学结构的变化.结果表明,腹腔注射菌液后可形成毒血症,兔大肠杆菌的发病率与内毒素呈正相关；随着肠绒毛长度和粘膜厚度的恢复,病兔逐渐恢复正常.乳酸菌素在大肠杆菌引起兔腹泻的治疗中能有效恢复肠壁厚度和绒毛长度,在疾病恢复期治疗效果好于庆大霉素.%In order to study the effect of E. Coli on structure of small intestine in rabbits and compare curative methods, forty rabbits were randomly divided into four groups. At different times endotoxin was detected and the structure changes of small intestine were observed and compared after injection of E. Coli by abdominal cavity. The results showed that intraperitoneal injection of bacilli could cause toxaemia. With the increase of the intestinal villi length and mucosa thickness rabbit recovered gradually. Lactolin could effectively restore the intestinal villi length and mucosa thickness, its effect on the lactolin group was better than that of gentamicin on the gentamicin group.
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