皖南地区支原体感染情况及药敏结果分析

摘要

目的:研究皖南地区支原体感染及药物敏感情况,指导本地区临床合理用药.方法:对2013年11月～2016年10月于我院皮肤性病科就诊的疑似非淋菌尿道炎(宫颈炎)的2166例患者支原体培养及药敏试验结果进行回顾性分析.结果:2166例受检对象中,检测出支原体感染1347例(62.19%),其中解脲支原体(Uu)阳性患者704例(32.50%),人型支原体(Mh)阳性患者65例(3.00%),Uu+Mh混合阳性患者578例(26.69%).女性支原体感染阳性率(67.29%)高于男性(54.68%),差异具有统计学意义(P<0.01).Uu阳性患者对强力霉素、美满霉素、克拉霉素最为敏感,Mh阳性患者对美满霉素、强力霉素最为敏感,Uu+Mh混合阳性患者对美满霉素、强力霉素最为敏感.结论:皖南地区支原体感染以Uu为主,其次是Uu和Mh混合感染,本地区支原体感染可首选美满霉素、强力霉素治疗.%Objective:To investigate the status of mycoplasma infection and its drug sensitivity in patients in the south area of Anhui province for evidence to plan rational medication.Methods:2166 cases of suspected non-gonococcal urethritis(cervicitis) diagnosed in our department were included from November 2103 through October 2106.All patients underwent culture of the mycoplasma and drug sensitivity tests,and the results were reviewed.Results:1347 cases (62.19%) in 2166 were confirmed mycoplasma infection.704 cases (32.50%) were associated with ureaplasma mycoplasma (Uu) infetion,65(3.00%) with mycoplasma hominis (Mh) infetion,and 578 (26.69%) with mixed Uu and Mh infection.Females had higher mycoplasma infection rate than males(67.29% vs.54.68%),with significant difference(P<0.01).Patients with positive Uu were the most sensitive to doxycycline,minocycline and clarithromycin,and those of positive Mh were more sensitive to minocycline and doxycycline.Patients with mixed Uu and Mh results were sensitive to the minocycline and doxycycline.Conclusion:Uu appears the major pathogen of mycoplasma infection,followed by mixed Uu and Mh in patients living in the south area of Anhui province,and minocycline and doxycycline may be the first line of drugs for mycoplasma infection.