Microencapsulation-based technologies for the double fortification of salt with iron and iodine.

摘要

Iron premix formulations were prepared by agglomerating ferrous fumarate via extrusion, followed by colour-masking with titanium dioxide and microencapsulation with polymer coatings. The fluidized-bed coating process was determined to be a feasible technique to encapsulate the premix particles. Seven encapsulants at various encapsulation levels were investigated. Double-fortified salt samples were prepared by blending iron premix with two types of iodized salt and were stored at 35°C and 60% R.H. for three months to determine their stability.;The DFS samples made with dry salt retained more than 90% of the iodine and more than 94% of the ferrous iron after three months. Hydrophilic coatings such as HPMC offered more protection at the 10% encapsulation level compared to soy stearine. However, in moist salt, high encapsulation levels of soy stearine offered the best barrier between iron and iodine. All premix formulations exhibited high particle density, good bioavailability and acceptable appearance.