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A computational model for particulate matter transport and deposition in the human nasal airway.

机译:颗粒物质在人鼻气道中运输和沉积的计算模型。

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摘要

As the interface between the human respiratory system and the environment, the nose plays many vital roles. Not the least of which is filter. Resulting from numerous natural and anthropogenic processes, particulate matter becomes airbome. Should particulate matter reach the lower portions of the respiratory tract, a host of maladies may occur. In an attempt to further understand the physics behind particulate matter transitioning from the environment into humans a computational model has been developed to predict the efficiency with which human noses can remove particles before they reach the lungs. To this end computational fluid dynamics and Lagrangian particle tracking simulations have been run to gather information on the deposition behavior of both spherical and ellipsoidal particles. As a result the key features driving impaction in the nose have been identified. Empirical models have been proposed and shown to work for a variety of simplified and anatomical nasal geometries.
机译:作为人类呼吸系统与环境之间的界面,鼻子扮演着至关重要的角色。最重要的是过滤器。由于许多自然和人为的过程,颗粒物变成了空气微粒。如果颗粒物到达呼吸道的下部,则可能会发生许多疾病。为了进一步理解颗粒物从环境转变为人类的物理原理,人们开发了一种计算模型来预测人的鼻子在进入肺部之前可以清除颗粒的效率。为此,已经进行了计算流体动力学和拉格朗日粒子跟踪模拟,以收集有关球形和椭圆形粒子沉积行为的信息。结果,已经确定了驱动鼻子撞击的关键特征。已经提出了经验模型,并且显示了经验模型可用于多种简化的和解剖的鼻部几何形状。

著录项

  • 作者

    Shanley, Kevin T.;

  • 作者单位

    Clarkson University.;

  • 授予单位 Clarkson University.;
  • 学科 Engineering Biomedical.;Engineering Mechanical.
  • 学位 Ph.D.
  • 年度 2009
  • 页码 130 p.
  • 总页数 130
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 生物医学工程;机械、仪表工业;
  • 关键词

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