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Evaluation of a MapCHECK2(TM) Diode Array for High Dose Rate Brachytherapy Quality Assurance.

机译:为高剂量率近距离放射治疗质量保证评估MapCHECK2(TM)二极管阵列。

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摘要

Despite continuous improvements in design of HDR brachytherapy delivery systems, the position of the source is still verified only through the HDR afterloader hardware/software based on the length of the wire reeled out relative to the parked position. The position of the source is not independently monitored during the treatment, potentially opening the door to misadministrations. We investigate the feasibility of using dose maps acquired with a two-dimensional diode array to verify the relative source locations and confirm delivered dose during an HDR treatment.;Dose maps for the source located at selected distances in air and depths in solid water were acquired with a MapCHECK2(TM) diode array and the Varian VariSource(TM) Ir-192 HDR afterloader. The peak location of the measured dose profile for each dwell position provided the X and Y coordinates while the full width at half maximum (FWHM) of each peak was used to calibrate the source distance along the Z axis. Two treatment orientations were considered with the source moving along 1) the rectangular surface of a solid water phantom and 2) the inclined plane of a paraffin wax wedge to verify the method for both coplanar and non-coplanar source and detector geometries for three source positions. Acquired dose maps were used to restore coordinates of dwell positions.;Although the spatial resolution is 10 mm along a row or column of diode detectors, the accuracy in determining dwell position coordinates was found to be within +/-2 mm in the X and Y directions of the diode plane using a polynomial fit to interpolate the values at distances between the measured points. The FWHM was found to increase linearly with source depth/distance, making it a suitable parameter for determining the source Z coordinate. Our studies have verified that the dose maps can be used as a routine QA tool for HDR treatment delivery verification.
机译:尽管对HDR近距离放射治疗输送系统的设计进行了持续改进,但仍仅根据相对于停放位置的绕线长度,通过HDR后装载器硬件/软件来验证放射源的位置。在治疗过程中不会独立监视放射源的位置,这有可能为误用药物敞开大门。我们研究了使用二维二极管阵列采集的剂量图来验证相对源位置并确认HDR治疗期间所递送剂量的可行性。;获得了位于空气中选定距离和固体水中深度处的源的剂量图带有MapCHECK2(TM)二极管阵列和Varian VariSource(TM)Ir-192 HDR后装载器。提供了X和Y坐标,每个停留位置的剂量分布图的峰位置,而每个峰的半峰全宽(FWHM)用于校准沿Z轴的源距离。考虑了两个处理方向,其中源沿1)固体水体模的矩形表面移动; 2)石蜡楔的倾斜平面,以验证用于共面和非共面源的方法以及针对三个源位置的检测器几何形状。使用获得的剂量图来恢复驻留位置的坐标。尽管沿一排或一列二极管探测器的空间分辨率为10 mm,但在X和X轴上发现确定驻留位置坐标的精度在+/- 2 mm以内。使用多项式拟合将二极管平面的Y方向插值到测量点之间的距离处。发现FWHM随着源深度/距离线性增加,使其成为确定源Z坐标的合适参数。我们的研究已经证实,剂量图可以用作HDR治疗交付验证的常规质量检查工具。

著录项

  • 作者

    Macey, Nathaniel John.;

  • 作者单位

    The University of Toledo.;

  • 授予单位 The University of Toledo.;
  • 学科 Biomedical engineering.;Oncology.;Medical imaging.
  • 学位 M.S.
  • 年度 2015
  • 页码 118 p.
  • 总页数 118
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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