THE MAGNETOSTATIC FORCE PRODUCED BY CURRENT LOOPS AND ITS MEDICAL APPLICATIONS.

摘要

This dissertation studies the magnetostatic force on permeable bodies both theoretically and experimentally. Recent technological advances have been tremendously advantageous to the delivery of protein carrying biologically active substances. The use of magnetic fields has served as the driving force in a guidance system to transport these substances to specific sites within the living system. Spheres of protein approximately one micron in diameter, termed "microspheres" are impregnated with magnetite (Fe(,3)O(,4)) along with other desired substances, this combination of elements is then injected into the bloodstream. Once in the bloodstream they flow freely until the desirable site is reached. They then become localized in the capillaries where they are permanently attached to the capillary wall, and in some cases the magnetic reaction may cause the microsphere to penetrate the surrounding tissue. Once the microspheres are permanently attached, the magnetic field may be removed. The biological mechanisms of microspheres have been well established, but in order to accurately control the delivery of microspheres to specific sites, concentrated research on magnetic fields remains to be done. This thesis analyzes the magnetic fields and magnetostatic forces which are necessary in the control of microspheres. A theoretical analysis of the magnetostatic force due to current loops is made consisting of a systematic design and an experimental study involving the effects of magnetostatic forces on microspheres injected into animals.