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Prevalence of alcohol and drugs in second sample blood specimens from potentially impaired drivers in the Commonwealth of Virginia, 2001--2002.

机译:2001--2002年弗吉尼亚州潜在受损驾驶者的第二份血液样本中的酒精和药物普及率。

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摘要

Driving Under the Influence of Alcohol and/or Drugs has been an issue of public safety for many years. Studies have been performed to determine alcohol content in driver's blood. However, limited research has been performed to determine which drugs maybe present in drivers. The purpose of this research study was to identify if drugs were present, the blood concentration of the drug if identified, and any potential trends in drug use in drivers who had been arrested for suspected "driving under the influence of alcohol and/or drugs" in the Commonwealth of Virginia. The study attempted to identify the incidence of multiple drugs being present (single agent versus multi-drug use or abuse) in a driver that was arrested for a DUID offense. The study also attempted to determine if there was a blood alcohol concentration observed where alcohol was the only drug detected in the driver's blood sample at the time of arrest. From July 1, 2001 through December 31, 2002, 2948 blood samples from drivers who had been arrested for impaired driving, and had requested an independent analysis of their blood sample, were received and analyzed for blood alcohol content, and screened and quantitated for various illicit, prescription, and over the counter drugs. Presumptive positive results from the screening methods were qualitatively identified and quantitated. Initial screening was performed by immunoassay for assays that were commercially available (amphetamines, barbiturates, benzodiazepines, cannabinoids, cocaine, and opiates). Other screening was performed by gas chromatography or gas chromatography mass spectrometry. Alcohol was the most common drug detected, followed by cannabinoids, benzodiazepines, opiates, and cocaine. In approximately ½ of the samples, alcohol was the only drug detected. One in three samples contained 2 or more drugs, which may have impaired the driver's ability to operate a motor vehicle. Two or more drugs were detected throughout the range of blood alcohol concentrations. The range of drug concentrations from samples collected in 2001--2002 were compared to samples collected from 1990--1999. The concentration range of specific drugs detected did not change significantly between the two sample groups. The only significant change observed was that the average number of yearly samples received appeared to have increased ∼250 % per year.
机译:多年来,在酒精和/或毒品影响下驾驶一直是公共安全问题。已经进行了研究以确定驾驶员血液中的酒精含量。但是,已经进行了有限的研究来确定驾驶员中可能存在哪些药物。这项研究的目的是确定是否存在毒品,是否发现毒品的血药浓度以及因涉嫌“在酒精和/或毒品影响下驾驶”而被捕的驾驶员的毒品使用的任何潜在趋势。在弗吉尼亚联邦。这项研究试图确定在因DUID犯罪被捕的驾驶员中存在多种药物的发生率(单种药物还是多种药物的使用或滥用)。该研究还试图确定在被捕时驾驶员的血样中唯一检测出的毒品中是否观察到血液中的酒精浓度。从2001年7月1日到2002年12月31日,从因驾驶不便而被逮捕并要求对他们的血液样本进行独立分析的驾驶员那里收集了2948份血液样本,并对其血液酒精含量进行了分析,并对各种血液进行了筛查和定量分析。非法,处方药和非处方药。定性鉴定和定量筛选方法的推定阳性结果。最初的筛选是通过免疫测定法进行的,用于可商购的测定法(安非他命,巴比妥酸盐,苯并二氮杂,大麻素,可卡因和鸦片剂)。其他筛选通过气相色谱法或气相色谱质谱法进行。酒精是最常见的毒品,其次是大麻素,苯二氮卓,阿片和可卡因。在大约1/2的样品中,酒精是唯一检测到的药物。每三个样本中就有一个包含2种或更多药物,这可能会损害驾驶员的驾驶能力。在整个血液酒精浓度范围内检测到两种或多种药物。将2001--2002年收集的样本与1990--1999年收集的样本中的药物浓度范围进行了比较。在两个样品组之间,检测到的特定药物的浓度范围没有明显变化。观察到的唯一重大变化是,每年收到的平均样本数量似乎每年增加约250%。

著录项

  • 作者

    Wolf, Carl Edward, II.;

  • 作者单位

    Virginia Commonwealth University.;

  • 授予单位 Virginia Commonwealth University.;
  • 学科 Health Sciences Toxicology.
  • 学位 Ph.D.
  • 年度 2005
  • 页码 101 p.
  • 总页数 101
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 毒物学(毒理学);
  • 关键词

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