Global gene expression monitoring with microarrays provides a vast amount of biological information. Computers play a central role in many aspects of microarray analysis, including the layout design of customized arrays that can be used by printing robots to create customized microarrays for a myriad of different systems. We have developed an integrated software called "MIDAR" that provides optimized design solutions for customized microarrays based on user specified inputs. These include the genes and gene groups, the number of replicates and the type of chip design (oligo or cDNA). Users can additionally associate experimental data to stored chip designs. This readily provides researchers with the gene expression level, and an interactive image map that allows the user to view the included oligo/primer detail information and list specific data details for each spot. MIDAR incorporates the Gene Ontology (GO) database to provide for selection of genes based on a common characteristic such as biological function, molecular process, and cellular component. (Abstract shortened by UMI.)
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