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Mechanical properties of human middle ear tissues.

机译:人类中耳组织的机械性能。

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摘要

In this dissertation, mechanical properties of four middle ear tissues: tympanic membrane or eardrum, stapedial tendon, tensor tympani tendon and anterior malleolar ligament, were reported through experimental measurement and modeling analysis. The mechanical experiments with the aid of digital image correlation method were used to measure the stress-strain relationship, stress relaxation function, and ultimate or failure stress and strain of these middle ear tissues. The experimental results were further analyzed by finite element modeling and material modeling analysis with nonlinear hyperelastic models, the Ogden model and the modified Ogden model, to derive constitutive equations of investigated tissues. The viscoelastic properties of four middle ear tissues were reported for the first time in literature.; The geometric information of four middle ear tissues were also obtained through the image measuring technique and listed with statistic significances in Chapter 3. The mechanical properties of these middle ear tissues were then summarized and differences among them were explained based on their micro-structures and functions in Chapter 6.; Mechanical properties of four middle ear tissues were then employed in a published 3-dimensional finite element model of human ear with an accurate geometric configuration to investigate the transfer function of human middle ear in ligament related pathological conditions. The model predicted results were compared with temporal bone experimental data, and a good agreement between modeling results and experimental data were observed.; The major contribution of this study is to provide new and useful data on mechanical properties of middle ear tissues in literature. The results can be used for the theoretical analysis of human middle ear function under the normal or pathological conditions.
机译:本文通过实验测量和模型分析,报道了鼓膜或鼓膜,骨肌腱,张量鼓膜肌腱和前踝韧带四个中耳组织的力学性能。借助数字图像相关方法进行的机械实验用于测量这些中耳组织的应力-应变关系,应力松弛函数以及极限或破坏应力和应变。通过非线性超弹性模型,Ogden模型和改进的Ogden模型的有限元建模和材料建模分析,进一步分析了实验结果,从而得出了被研究组织的本构方程。文献首次报道了四种中耳组织的粘弹性。还通过图像测量技术获得了四种中耳组织的几何信息,并在第3章中列出了统计学意义。然后总结了这些中耳组织的机械性能,并根据它们的微观结构和功能解释了它们之间的差异。在第6章中;然后将四个中耳组织的机械性能用于已发布的人耳3维有限元模型中,该模型具有精确的几何构型,以研究人中耳在韧带相关病理情况下的传递功能。将模型预测结果与颞骨实验数据进行比较,观察结果与实验数据吻合良好。这项研究的主要贡献是在文献中提供有关中耳组织力学特性的新的有用数据。该结果可用于正常或病理条件下人中耳功能的理论分析。

著录项

  • 作者

    Cheng, Tao.;

  • 作者单位

    The University of Oklahoma.;

  • 授予单位 The University of Oklahoma.;
  • 学科 Health Sciences Audiology.; Engineering Biomedical.; Biology Physiology.
  • 学位 Ph.D.
  • 年度 2007
  • 页码 155 p.
  • 总页数 155
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 耳科学、耳疾病;生物医学工程;
  • 关键词

  • 入库时间 2022-08-17 11:40:34

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