声明
Abstract
摘要
CONTENTS
List of Tales
List of Figures
List of Abbreviations
1 Introduction
1．1 Organic Fluorescent Materials
1．1．1 Basic Principle of Fluorescence in Organic Materials
1．2 Aggregation caused quenching feature (ACQ)
1．3 Aggregation-induced emission feature (AIE)
1．3．1 AIE Working Mechanism
1．3．2 AIE-gen systems
1．3．3 Technological Applications
1．4 Stimuli Responsive Fluorescent Organic Gel
1．4．1 Metal Organic supramolecular Gel
1．4．2 Applications
1．5 Thesis Objectives
2 Development of Tunable Fluorophores via Isobutylene Bis-naphthylamide Cores：As a New AIE-Active Family
2．1 Introduction
2．2 Experimental Section
2．2．1 Material and instruments
2．2．2 Synthesis of fluorophore 1-AB
2．2．3 Synthesis of fluorophore 2-AN
2．2．4 Synthesis of fluorophore 2-AA
2．2．5 AIE experiments
2．3 Results and Discussion
2．3．1 Single crystal analysis and supramolecular interactions
2．3．2 Aggregation induced emission (AIE) property
2．3．3 Theoretical calculations (DFT／TD-DFT)
2．4 Summary
3 Two New Fluorescent Zn2+ Sensors Exhibiting Different Sensing Modes with Subtle Structural Changes
3．1 Introduction
3．2 Experimental Section
3．2．1 Instruments and reagents
3．2．2 Binding constants for receptors HL-1 and HL-2 towards Zn2+
3．2．3 Detection Limit of receptors HL-1 and HL-2 for Zn2+
3．2．4 Synthesis of compound HL-1
3．2．5 Preparation of HL-1-Zn
3．2．6 Synthesis of compound HL-2
3．2．7 Synthesis of compound HL
3．2．8 Preparation of sample solution for analysis
3．3 Results and Discussion
3．3．1 Fluorescence spectroscopic studies of HL-1 and HL-2 in the presence of various metal ions
3．3．2 Absorption spectroscopic studies
3．3．3 Partial 1H NMR of HL-1 and HL-2 with Zn2+
3．3．4 ESI-MS analysis
3．3．5 Signalling mechanisms of Zn2+ ion with HL-2 and HL-1
3．4 Summary
4 Aggregation-Induced Emission (AIE) Fluorophore Exhibits a Highly Ratiometric Fluorescent Response to Zn2+ in vitro and in Human Liver Cancer Cells
4．1 Introduction
4．2 Experimental section
4．2．1 Materials and instrumentation
4．2．2 UV-Vis and fluorescence measurements
4．2．5 Theoretical method (DFT and TD-DFT)
4．2．7 MTT assay
4．2．8 Synthesis of fluorophore 8AQ
4．2．9 Synthesis of compound 8WB
4．3 Results and Discussion
4．3．1 Single crystal structure and supramolecular interactions
4．3．2 Aggregation-induced emission (AIE) behavior of fluorophore 8AQ
4．3．3 Absorption spectroscopic smdies of 8AQ with various metal ions
4．3．4 Fluorescence response of fluorophore 8AQ with various metal ions
4．3．5 1H NMR titration of fluorophore 8AQ with Zn2+ to study the binding mode and composition of metal complex 8AQ-Zn
4．3．6 ESI-MS experiment
4．3．7 Theoretical calculation (DFT／TD-DFT) methods
4．3．8 Signaling mechanism of fluorophore 8AQ with Zn2+
4．3．9 Biological cell-permeability of 8AQ and intracellular ratiometic fluorescence response towards Zn2+
4．3．10 MTT assay
4．4 Summary
5 A Novel Smart Supramolecular Organic Gelator Exhibiting Dual-channel Responsive Sensing Behaviours towards Fluoride ion via Gel-Gel State
5．1 Introduction
5．2 Experimental Section
5．2．1 Materials and reagents
5．2．2 Gelation test
5．2．4 Detection limit of supramolecular metal organic gel OG-Zn for F-
5．2．5 Synthesis of gelator G-16
5．3 Results and Discussion
5．3．2 Fluorescence response of OG towards metal ions
5．3．3 Fluorescence response of OG and OG-Zn towards anions
5．3．4 Self-assembly mechanism in OG and OG-Zn
5．3．5 Stimuli responsive mechanism of OG and OG-Zn towards fluoride ion
5．3．6 Morphological studies of OG，OG-Zn，OG-Zn-F and OG-F
5．3．7 Rheological studies
5．4 Summary
6 Conclusion
Innovation Points and Future Horizons
Innovation Points
References
Published Academic Articles during PhD Period
Supplementary Materials
Acknowledgement
About the Author
