Urinary stone analysis with Fourier Transform Infrared spectroscopy(520 cases)

摘要

Urinary stone analysis is important technology in determining the possible etiology and the pathophysiology of stone formation.A better understanding of the stone composition may be helpful in preventing urinary stone formation.From September 2009 to December 2011,520 urolithiasis patients from Urology Department in Wuhan Tongji Hospital after surgery treatment or after shock wave lithotripsy, or after stones spontaneous passage were taken part in the study.Stone compositional analysis was performed using fourier transform infrared spectroscopy.The results showed that themost frequent composition in 173 pure stone (33.3％) was calcium oxalate (19.8％),followed by calcium phosphate (9.2％),xantine (2.5％),L-cystine(1％),silica (0.4％),uric acid (0.2％) and quartz (0.2％).347 (66.7％) were mixed stone,calcium oxalate was the most commonly major component(34％), followed by calcium phosphate (22.7％), uric acid and cystine.In our case,the most commonly found pure stone was calcium oxalate,while the most frequent mixed stone was calcium oxalate and calcium phosphate mixture.The relationship between stone location,gender,age and stone components were showed.We present some results of analysis of urinary tract stones extracted from patients using FTIR spectroscopy and show specific features of urinary tract stone composition and may help improve understanding of the urolithiasis pathophysiology.

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英文摘要

Part I. Urinary stone analysis with Fourier Transform Infrared spectroscopy（520 cases）

REVIEW Urinary tract stone disease: Pathogeny, evaluation, diagnostic and medical treatment.

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