Based on these results, antibiotic-loaded chitosan demonstrates the potential to serve as a suitable coating for orthopaedic and dental/craniofacial implants. Elution tests revealed rapid drug release profiles for both chitosan materials tested, with the 78% DDA chitosan having the more rapid release of gentamicin. Future work includes mechanical testing to quantify the adhesion of the coating at the metal-coating interface. There is also a need to test the effects that crosslinking would have on the drug release profile.
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