Risk of dying among tuberculosis patients

摘要

Tuberculosis (TB) is one of the first worldwide 10 causes of disease. Diminishing mortality risk by TB is an important indicator of successful TB control in society. We conducted a survey from January 1998 to December 2004 on 100 patients who died in Cluj Napoca Pneumology Clinical Hospital by comparison with a second group of 120 TB patients with a favourable evolution. We introduced in the study patients confirmed with TB diagnosis, without coexistence of HIV+ status or any malignancy. We analyzed influence of age, gender, area of residence, smoking status, alcohol abuse, family and environment TB history on Tb resolution outcomes. Special consideration was given to radiological findings, main causes of death,, treatment regimens and compliance. Statistical data with analysis of the two groups included in the study aimed to reveal most important mortality risk factors in TB patients and assessment of the relative risk. We found higher mortality in TB patients with concurrent disorders and lack of compliance with an OR of 11.84 as another important risk to increase TB mortality. We concluded identification of risk factors for mortality among TB patients can improve the management ofTB cases and avoid increased mortality in such patients.