Low Level Pulsed Radio Frequency Field and Its Remedial Effect on Osteoporosis and Bone Fracture

摘要

It is widely accepted that bone remodeling is dependent on electrical stimulation. In the present investigations applying noninvasive,pulsed electric stimulation (carrier frequency 14 MHz,Modulated at 16 Hz of amplitude 10 V peak to peak),coupled capacitively to the induced osteoporotic rat bones. We observed that the electrical stimulation significantly increased the calcium,phosphorus and carbon content compared to contralateral sham exposed limb bones. A similar treatment of electromagnetic energy on an induced fracture in rats (0.5 cm gap in tibia) is found to accelerate the healing process. For this both the sides of the tibia were subjected to fracture,where only one is provided electrical stimulation (experimental). By comparing the ultrasonic attenuation in control and experimental portion of the leg in the same rat,it is verified that healing is faster in the later. This further confirms that stimulated side showed greater bone mass than the contralateral position. Efficacy of this technique in the two related clinical conditions is thus established.