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Novel approach to modeling spectral-domain optical coherence tomography with Monte Carlo method

机译:用蒙特卡洛方法建模谱域光学相干层析成像的新方法

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Numerical modeling Optical Coherence Tomography (OCT) systems is needed for optical setup optimization, development of new signal processing methods and assessment of impact of different physical phenomena inside the sample on OCT signal. The Monte Carlo method has been often used for modeling Optical Coherence Tomography, as it is a well established tool for simulating light propagation in scattering media. However, in this method light is modeled as a set of energy packets traveling along straight lines. This reduces accuracy of Monte Carlo calculations in case of simulating propagation of dopeds. Since such beams are commonly used in OCT systems, classical Monte Carlo algorithm need to be modified. In presented research, we have developed model of SD-OCT systems using combination of Monte Carlo and analytical methods. Our model includes properties of optical setup of OCT system, which is often omitted in other research. We present applied algorithms and comparison of simulation results with SD-OCT scans of optical phantoms. We have found that our model can be used for determination of level of OCT signal coming from scattering particles inside turbid media placed in different positions relatively to focal point of incident light beam. It may improve accuracy of simulating OCT systems.
机译:需要光学建模光学相干断层扫描(OCT)系统来优化光学设置,开发新的信号处理方法以及评估样品内部不同物理现象对OCT信号的影响。蒙特卡洛方法通常被用于光学相干断层扫描的建模,因为它是用于模拟光在散射介质中传播的成熟工具。然而,在这种方法中,光被建模为一组沿直线传播的能量包。在模拟掺杂传播的情况下,这降低了蒙特卡洛计算的准确性。由于此类光束通常在OCT系统中使用,因此需要修改经典的蒙特卡洛算法。在介绍的研究中,我们结合了蒙特卡罗方法和分析方法,开发了SD-OCT系统模型。我们的模型包括OCT系统的光学设置的属性,在其他研究中通常会省略这些属性。我们提出了应用的算法,并通过光学体模的SD-OCT扫描比较了仿真结果。我们已经发现,我们的模型可以用于确定OCT信号的电平,该电平来自混浊介质内部的散射粒子,这些介质位于相对于入射光束焦点的不同位置。它可以提高模拟OCT系统的准确性。

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