EVALUATION OF PHOTOSENSITIZERS SINGLET OXYGEN PRODUCTION FOR PHOTODYNAMIC THERAPY APPLICACTIONS USING TIME RESOLVED THERMAL LENS

摘要

We report on the optical characterization and measurement of oxygen singlet quantum yield of Chlorophyll and Chlorin e_6 in water-ethanol mixtures by direct observation of thermal relaxation using time resolved thermal lens method. The analysis of the time-resolved curve allows the determination of the quantum yield of singlet oxygen formation. The quantum yield is deduced from the relative magnitudes of the fast and slow components.