Phthalocyanine photosensitizers for photodynamic therapy and their synthesis and use (Phthalocyanine Photosensitizers for Photodynamic Therapy and Methods for Their Synthesis and Use)

摘要

The present invention relates to a novel series of phthalocyanine compositions (or compounds) useful as photosensitizers in photodynamic therapy. In particular, the present invention relates to a novel series of aluminum (Al) and / or silicon (Si) phthalocyanines having substituted amines or quaternary ammonium axial ligands bound to a central metal, and novel phthalocyanines To the use of the composition. The present invention also relates to a method of preparing such a composition for use in photodynamic therapy.