Effect of multiple scattering on the accuracy of velocity profile reconstruction from the Monte Carlo simulated OCDT signal in a model of biological tissues

摘要

Using the Monte-Carlo method we simulated the Optical Coherence Doppler Tomography (OCDT) signals at the wavelength of λ = 822 nm from one and two plain flows of a non-aggregating particulate suspension mimicking blood embedded into a stationary light scattering medium (2% Intralipid solution) with optical properties close to those of human skin. The dependences of statistical characteristics such as mean value and standard deviation of the stochastic fluctuations of the Doppler frequency behind the first flow (Doppler noise) on the angle between the direction of incident radiation and the normal to the object surface (Doppler angle) were studied. It was shown that with the increase of Doppler angle the mean value of Doppler Noise as well as its standard deviation decrease. It was shown that with an increase of embedding depth of the flow the reconstructed velocity values become smaller than the predefined ones and the reconstructed profile is stretched towards the rear border. In the case of two flows, it was shown that with an increase of the first flow velocity the reconstructed velocity values of the second flow increase too. The computer with multiprocessor architecture was used for Monte-Carlo simulation.