Association between Risk of Metabolic Syndrome and the Level of the ACE in Security guards- a cross-sectional study

摘要

Introduction: The working characteristics of security guards include shift work and work long hours, stay in monotonous work and sedentary for a long time, which can easily lead to lower physical activity, risk factors for cardiovascular diseases, little knowledge exists about the association between risk of Metabolic Syndrome (Mets) and the Level of the advanced glycation end products (AGEs) in security guards. Many previous studies show the contribution of AGEs in the origin and progression of certain chronic diseases, as well as Mets. Mets is a high-prevalent metabolic disorder characterized by hypertension, central (abdominal) obesity, hypertriglyceridemia, low HDL-cholesterol, and/or increased fasting glucose. Objectives: The objective the present study was to examine the association between skin autofluorescence (SAF) AGEs and the prevalent of Mets in security guards. Study population was composed of 144 security guards and 66 administration workers. The components of metabolic syndrome were measured by physical examination, and the level of AGE were evaluated by SAF. Data analyses were performed in 2018 using SPSS software version 22. Continuous variables were measured by t-test and categorical variables were measured by chi-square test. The odds ratios(OR) of risk component of metabolic syndrome were measured by logistic regression. Results: There was a substantial difference in the prevalence of Mets between security guards and administration staff. Notably, 45.1% of the security guards have metabolic syndrome while 16.7% of the administrative staff have metabolic syndrome. Additionally, in the mean of level of AGE, security guards had higher mean skin autofluorescence than the administrative staff (2.7±1.0 AU versus 2.2±0.7 AU). Conclusion: The security guards have higher risk of metabolic syndrome and the higher level of AGEs than the administration staff. There are a positive association between skin autofluorescence (SAF) AGEs and the prevalent of Mets.