Photoinactivation of bacteria of P. Aeruginosa: role of light coherence

摘要

Influence of laser irradiation and low-coherent speckles on the colonies grows of Pseudomonas Aeruginosa is studied. It has been demonstrated that effects of light on the inhibition or re-activation of cells are connected with speckle dynamics. Role of temporal coherence of light at photoinactivation of bacteria is studied. The regimes of cell suspension perfusion with purpose of devitalization of bacteria are found on the base of experimental investigations. Mathematical model of interaction of low-coherent laser radiation with bacteria suspension has been developed. Parameters of mathematical model have been identified on the base of experimental researches. Computer simulations of the processes of laser-cells interaction have been carried out.