A Bacterial Swarm Algorithm to Control Drug Release by Multi-Nanorobots

摘要

This paper presents a Bacterial Swarm Algorithm (BSA) to control the drug release in the process of targeting drug delivery by multi-nanorobots cooperation. On one hand, the algorithm can control the number of nanorobots at the target area. Based on the principle of bacteria quorum sensing, the number of nanorobots at the target area is judged by themselves with the help of a chemical substance called AI released by the nanorobots. If the concentration of AI achieves a certain threshold, the nanorobots will leave the target by chemotactic operation, which prevents the blockage of blood vessels. On the other hand, the drug molecular weight released by the nanorobots can be adjusted by the algorithm, so the drug concentration is controlled effectively. The feasibility of the proposed BSA has been verified by simulation results.