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CORONARY VENOUS BYPASS GRAFT FAILURE, HEMODYNAMIC PARAMETERS INVESTIGATION

机译:冠状动脉静脉旁路接枝衰竭,血流动力学参数调查

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The purpose of this paper was to investigate the hemodynamic parameters associated to the blood flow in failed coronary venous bypass graft using computational fluid dynamics (CFD) technique. Narrowed section creates bypass graft constriction. This change of the flow direction alters significantly the local hemodynamic parameters. In this paper, a patient specific three-dimensional bypass model is used to simulate blood flow in narrowed venous bypass graft for understanding the detailed flow physics of transition to turbulence downstream of the graft curvature and the narrowed section. In conclusion, successive curvature and sudden narrowing of the bypass graft induce disturbance of the flow profile that produce high local WSS and large recirculation regions. Both this parameters create favorable conditions to the initiate the graft failure.
机译:本文的目的是使用计算流体动力学(CFD)技术来研究与失败的冠状动脉旁路移植物相关的血流动力学参数。缩小部分创造旁路移植收缩。流动方向的这种变化显着改变了本地血液动力学参数。在本文中,患者特定的三维旁路模型用于模拟变窄的静脉旁路移植物中的血流,以了解移植曲率下游的过渡到湍流的详细流动物理学和变窄部分。总之,旁路移植物的连续曲率和突然缩小诱导产生高局部WSS和大型再循环区域的流动曲线的扰动。这两个参数都会为发起移植失败创造有利条件。

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