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CORONARY VENOUS BYPASS GRAFT FAILURE, HEMODYNAMIC PARAMETERS INVESTIGATION

机译:冠状静脉旁路移植术失败,血液动力学参数研究

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The purpose of this paper was to investigate the hemodynamic parameters associated to the blood flow in failed coronary venous bypass graft using computational fluid dynamics (CFD) technique. Narrowed section creates bypass graft constriction. This change of the flow direction alters significantly the local hemodynamic parameters. In this paper, a patient specific three-dimensional bypass model is used to simulate blood flow in narrowed venous bypass graft for understanding the detailed flow physics of transition to turbulence downstream of the graft curvature and the narrowed section. In conclusion, successive curvature and sudden narrowing of the bypass graft induce disturbance of the flow profile that produce high local WSS and large recirculation regions. Both this parameters create favorable conditions to the initiate the graft failure.
机译:本文的目的是使用计算流体力学(CFD)技术研究失败的冠状静脉旁路移植物中与血流相关的血液动力学参数。狭窄的部分会造成旁路移植物狭窄。流动方向的这种变化显着改变了局部血液动力学参数。在本文中,使用患者特定的三维旁路模型来模拟狭窄静脉旁路移植物中的血流,以了解在移植物曲率和狭窄部分下游向湍流过渡的详细流动物理学。总之,旁路移植物的连续曲率和突然变窄会引起流动剖面的扰动,从而产生较高的局部WSS和较大的再循环区域。这两个参数都为引发移植失败创造了有利条件。

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