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Permeation Studies on Freshly Excised Rat Gastric Mucosa: Influence of pH

机译:新切除的大鼠胃粘膜渗透研究:pH值的影响

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摘要

The objective of this study was to evaluate the influence of pH on the permeation of model drugs through freshly excised rat stomach. Additionaly, the capability of the gastric mucosa to maintain an acidic pH ex vivo was assessed. Cell viability was controlled throughout all studies via histological examinations.
机译:本研究的目的是评估pH对模型药物通过新切除的大鼠胃部渗透的影响。辅助,评估胃黏膜以维持酸性pH离体的能力。通过组织学检查在整个研究中控制细胞活力。

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