A 2-D Simulation of Hydrocephalus in the Foramens of Monro of the Human ventricular System

摘要

This study investigates the Cerebrospinal fluid(CSF) flow behavior in a two-dimensional plane(2-D)of the human ventricular system when the hydrocephalus in the Foramens of Monro(F.O.M) occurs.In order to understand the CSF behaviour when the hydrocephalus occurs,it is essential to comprehend its normal flow dynamics i.e.the healthy case with no hydrocephalus.This had been done numerically by reconstructing the ventricular system geometry from the MRI scans and then made a 15° degree cut in the surgical line to obtain the outlines of the 2-D plane.The healthy cases were solved for the CSF actual flow rate,which is between 100-500 ml/day in 100 incremental steps.The unhealthy cases were studied for the average flow rate,which is 300 ml/day but for blockage ratios of the Foramen diameter of 20%,50%and 75%.These obstructions are designed to simulate the hydrocephalus.The results show that as the flow rate increases the pressure and the velocity values increases,but no changes in the flow pattern occurs.The maximum pressure on the normal cases occurred in the lateral ventricles and the maximum velocity occurred in the aqueduct neck.The results of the hydrocephalus cases show that as the obstruction degree increases the pressure in the lateral ventricle increases accompanied with a velocity increase in the obstructed Foramen,which may cause unwanted stress on the neighboring tissues.