The Classification of Metastatic Bone Disease with Multifractal Analysis of Microscopic Images

摘要

In this paper is presented the method, based on multi-fractal (MF) analysis, for classifying the shape of tissue cells from microscopis images, which identifies the primary cancer in cases of metastasis bone disease. This method can be applied as an additional and objective tool in primary cancer diagnosis, as well as in decreasing of subjective factor and error probability. The method is tested over a large number (1050) of clinical cases from the Institute of Pathology, University of Belgrade. The results of computer-aided analysis of images have been presented and discussed.