In these days, nitric oxide (NO), carbon monoxide (CO) and hydrogen sulfide (H_2S) are well known as endogenous neurotransmitters in mammalian cells and have been studied regarding their mechanisms playing the roles as neurotransmitters in vivo. However, the actual relations among these three gases in transmitting neuronal signals in brain are still controversial and therefore, direct realtime concurrent analysis of NO, CO and H_2S is required to clarify their biological relations.
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