Quartz Crystal Microbalance Aptasensor for the Molecular Detection of Dengue Virus

摘要

Dengue fever is the major public health concern in the Philippines and is endemic in all regions of the country in which all serotypes are present. Despite the widespread nature of the virus transmitted by mosquitos, molecular diagnostics have significant limitations. An early diagnosis of dengue may prevent severe clinical complications associated with the infection. A novel genosensor using an aptamer for the detection of dengue virus serotypes 1-4 was demonstrated in this study.