Formulation and Evaluation of Suppositoria Supplies Extract of Pinang Seeds (Areca catechu L.) as Anthelmintik

摘要

Areca palm is a type of palm and is commonly found in India, Malaysia, Taiwan, Indonesia and other Asian countries, both individually and in populations (Jaiswal wt al, 2011). The pharmacological potential of Areca catechu is one of its benefits as an anthelmintic. Part taken from areca nut for anthelmintic treatment is the seeds (cement), one of the ingredients that can be potential as a worm medicine from areca nut is the secondary metabolite compound Tannin which can inhibit and kill the larval activity or adult worms Ascariasis lumbricoides at a concentration of 20%, 30% and 40% betel nut extract. (Fania Putri Luhurningtyas, 2013). The purpose of this study was to formulate and evaluate suppository preparations of areca nut extract as an anthelmintic using a cacao oleum fat base combined with cera alba. The evaluation carried out was organoleptic test, melting time, weight uniformity and storage stability test at room temperature. The results of the study explained that areca nut extract could be made in suppository preparations with good physical properties as suppository preparations with anthelmintic activity.