Antifungal activity of polymorphonuclear leucocytes on paracoccidiodides brasiliensis

摘要

Paracoccidioides brasiliensis is the causative agent of paracoccidioidomycosis. one of major systemic mycoses in Latin Materic and also an imported mycosis in Japan. P. brasiliensis is thermally dimorphic and grows as a yeast form in host tissues. Although polymorphonuclear leucocytes (PMN) are apparently involved in host inflammatory responses to this fungus, the possible role of PMN in host defesnse against this fungus has not yet been fully defined.